4. October 30, 2016 at Tampa Bay Buccaneers
During the 2016 NFL season, Khalil Mack put together one of the all-time defensive seasons of any player to ever play the game. Not only was he named NFL Defensive Player of the Year in 2016, but he also coming off a season where he was a First-Team All-Pro selection at both defensive end, and linebacker, becoming the first player to win that honor at two positions.
In a game against the Tampa Bay Buccaneers in late October, Mack put together a performance around Halloween that certainly scared Bucs fans. Mack racked up six tackles against Jameis Winston and company, getting to the quarterback on multiple occasions, as he racked up two sacks in the game.
That performance was in the middle of an eight-game stretch that saw Mack get at least one sack in each contest. No doubt that run led to him being named the DPOY, and at only 25-years old, the sky was the limit for what this devastating defensive player could do to any offense, at any time. Oakland won the game, and would win four more after that in a row, during a six-game winning streak.